Glucophage Uses, Dosage & Side Effects.

What is glucophage tablet?

Glucophage (metformin) is an oral diabetes medicine that helps to lower your blood glucose to as normal a level as possible.

Glucophage uses:

Glucophage is used as the first line treatment of diabetes. It belongs to a group of medicines called biguanides. Insulin is a hormone produced by the pancreas that makes your body takes in glucose (sugar) from the blood. Your body uses glucose to produce energy or stores it for future use. If you have diabetes, your pancreas does not make enough insulin or your body is not able to use properly the insulin it produces. This leads to a high level of glucose in your blood. Glucophage helps control blood sugar levels. If you are an overweight adult, taking glucophage over a long period of time also helps to lower the risk of complications associated with diabetes.

How to take glucophage:
Take glucophage with or after a meal. This will avoid u having side effects affecting your digestion. Do not crush or chew the tablet. Swallow each tablet with a glass of water.
  • If you take one dose a day, take it in the morning (breakfast) or if you take two doses a day, take them in the morning (breakfast) and evening (dinner)
  • If you take three divided doses a day, take them in the morning (breakfast), at noon (lunch) and in the evening (dinner) if, after some time, you think that the effect of glucophage is too strong or too weak, talk to your doctor or pharmacist.
If you have taken more glucophage than you should have, you may experience lactic acidosis. symptoms of lactic acidosis are vomiting, bellyache (abdominal pain) with muscle cramps, a general feeling of not being well with severe tiredness, and difficulty in breathing. If this happens to you, you may need immediate hospital treatment, as lactic acidosis may lead to coma. Contact a doctor or the nearest hospital straight away.

Usual dosage of glucophage 
Adult, children 10 years and over and adolescent usually start with 500mg with breakfast for at least one week then 500 mg with breakfast and evening meal for at least one week, then 500mg with breakfast, lunch and evening meal or 850 mg every 12 hours with or after food, usual maximum 2g daily in divided doses.

Main side/adverse effects 
Like other medicines, glucophage can cause side effects, although not everybody gets them. The following side effects may occur:
  • Gastrointestinal adverse effects including anorexia, diarrhoea, dyspepsia, flatulence, nausea, vomiting.
  • Headache, metallic taste, weight loss 
  • Anaemia, megaloblastic, hypoglycemia, lactic acidosis, long time glucophage therapy may cause a decreased of vitamin B12 absorption with decreased of serum levels.


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